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STI Prevention Vaccines



Using condoms is key to preventing STIs. For high-risk individuals, there are vaccines and medication available at the clinic that help to prevent STIs.

Who are the vaccines for?

Vaccines may be offered to people who have factors that increase their risk, including those who:

  • Have multiple sexual partners
  • Have group sex
  • Have had a bacterial STI within the last 12 months
  • Have had close sexual contact with someone who has an STI
  • Have other circumstances or behaviours that may increase their risk of getting an STI

Vaccination is not limited to a particular gender, sexual orientation or relationship status. Eligibility is based on your individual circumstances and level of risk.

If you think you may be at increased risk, please discuss this with a clinician. They will assess your individual circumstances and advise whether you are eligible for vaccination.

Please note: We are unable to provide vaccines for travel purposes. For travel vaccinations, please contact your GP or a travel vaccination service.

How do I access these vaccines?

If you’re eligible and have visited the clinic for PrEP, you may receive a text inviting you to book an appointment for these vaccines.

You can also ask about these vaccines at your routine PrEP appointment or you can phone the clinic to find out of you’re eligible.

What vaccines are available?

MenB vaccine (gonorrhoea)

The Meningocococcal B (MenB) vaccine, also called Bexsero, is available for eligible individuals from September 2025. It gives a 30-40% protection against gonorrhoea. It requires two injections at least four weeks apart.


Mpox vaccine

Mpox (previously known as monkeypox), can be transmitted through sexual contact. The Mpox vaccine provides good protection against the mpox virus. It’s usually given as two injections at least 28 days apart.


Hep A vaccine

Two injections given 6-12 months apart to protect against Hepatitis A.


Hep B vaccine

Three injections to protect against Hepatitis B. Usually, the second injection is given one month after the first, and the final injection is given 6 months after the first.


HPV vaccine

Two injections taken at least six months apart. (Sometimes three vaccines are needed.) This vaccine is available for gay, bisexual, and other men who have sex with men who are up to, and including, 45 years of age.


Prevention medication

Alongside vaccines, if you visit the clinic and are high-risk, clinicians may offer you prevention medication. This includes:

  • PrEP (a pill you can take before sex that offers near complete protection from HIV).
  • PEP (a pill you take if you think you may have been exposed to HIV within the last 72 hours which may stop you becoming infected.)
  • DoxyPEP (a pill you take after sex to prevent syphilis).

Learn more about prevention medication